Definition: The adrenal gland is an essential part of the endocrine system and produces adrenaline. Humans and other mammals have two adrenal glands - one on top of each kidney; some vertebrates have more. Adrenaline helps us to respond to danger, fear or stress - in these moments, the adrenal gland produces more adrenaline, which it releases into the bloodstream. This adrenaline stimulates the heart to pump more quickly and the body to breathe more rapidly, which results in a greater intake of oxygen. It also makes more oxygen and glucose available to the brain and muscles, which helps with the 'fight or flight' response.